13 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... of SLE versus DIL ... Management #Summary #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle weakness, rash ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... #differential #diagnosis ... #comparison #rheumatology
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
A presumptive diagnosis ... #Clinical #Photo ... #Mandibularis #Rash ... #NEJM #Shingles
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... signs #symptoms #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... evidence of (fatigue, rash ... eruption - Butterfly rash ... Photosensitive rash ... Photosensitivity • Malar rash
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... #DIL #rheumatology ... #diagnosis #treatment
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
schistocytes, DIC ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... Differential Diaqnoses ... MAS, Visceral, DIC ... management #treatment #rheumatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
schistocytes, DIC ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison