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diagnosis hematology differential erythematosus systemic classification clinical dermatomyositis druginduced oncology product reactions signs skin symptoms syndrome treatment vasculitis activation acute
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... Positive in 60-80% of cases ... #sle #comparison
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Manifestations: Malar rash ... Positive in 60-80% of cases ... #Summary #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... • Special cases ... #rheumatology # ... pharmacology #levels #lupus ... #management
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... 6) An annular rash ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis(5%) Blood ... symptoms #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Rash - Differential ... : • Palpable Rash ... • Non-Palpable Rash ... : • Palpable Rash ... • Non-Palpable Rash
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... endothelium) & Decr blood
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... I see all of these ... features in most cases ... APML #Pathology #Hematology
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