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hematology thrombocytopenia obstetrics pregnancy liver oncology table algorithm causes hepatitis obgyn ttphus apml classification differentiation disease disorders fatty framework hemolyticuremicsyndrome
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... child * Severe cases ... #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
coagulation defects. 1) HELLP ... child * Severe cases ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential # ... diagnosis #icp # ... HELLP #AFLP
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Diagnosis Algorithm ... Autoimmune • ITP ... Non-lmmune: • HELLP ... #Causes #Hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltration) Differential ... Diagnosis: Viral ... Preeclampsia, HELLP ... Liver #Pregnancy #hepatology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... Diagnosis Framework ... Antibody-mediated: ITP ... - Pregnancy: HELLP ... #hematology
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... : TTP has high rates ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... • Pregnancy: HELLP ... #diagnosis #algorithm ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... PLT in selected cases ... Refractory ITP, ... #Workup #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
opacities • Diagnosis ... initiation • Differential ... Diagnosis: Infection ... organ dysfuxtion, ICU ... #management #hematology
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