1161 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased Aldosterone Release ... Decreased Renin Release ... Pathophysiology #Pharmacology
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Colchicine - Release ... pathophysiology #pharmacology
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Initiation - Immediate release ... Initiation - Extended release ... side effects from release ... #Dosing #CKD #pharmacology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Consider extended-release ... • Try extended-release ... Indications #Titration #Pharmacology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... triggering insulin release ... Sulfonylureas #Pharmacology
FDA-Approved 1st line Medications for Tobacco Cessation Treatment

Nicotine patch, Nicotine lozenge, Nicotine gum, Nicotine inhaler, Nicotine
Bupropion sustained release ... SR) (tablet) #Pharmacology
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Precipitants and Pharmacology ... Oxitriptan ↑ Serotonin Release ... Serotonin #Syndrome #Pharmacology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
treatments inhibits PTH release ... #Pharmacology #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Withdrawal seizure, relapse ... Pathophysiology #Psychiatry #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Aliskiren) • Renin release ... pathophysiology #pharmacology