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management differential syndrome neurology oncology algorithm clinical hepatology reactions rheumatology barre blood classification comparison guillain liver product skin table thrombocytosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... Inflammatory: • IBD ... effect following treatment ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Rebound effect from treatment ... #Differential #Diagnosis ... #Algorithm #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
: 70 years old, ... ~10,000 new cases ... transformation to acute ... #Management #treatment ... #hematology #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... #Differential #Diagnosis ... Classification #Nephrology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... months without treatment ... Drug-Induced Liver Injury ... gastroenterology #management #diagnosis
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
may be normal in mild ... cases) • PT/INR ... - Acute Bleeding ... #Management #treatment ... #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... for alternative causes ... dechallenge • Acute ... #hepatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
HELLP Syndrome and Acute ... the critically ill ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... • SJS/TEN • Acute ... withdrawal • Mild ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Ischemic Liver, IBD ... coagulation and other causes ... Vasculitis • Injury ... pathophysiology #hematology
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