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diagnosis rheumatology differential management erythematosus ana hematology antibodies signs symptoms workup causes classification disease disorders neurology patterns sjogrens treatment vasculitis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
(SLE), Mixed connective ... (SLE), Sjogren's ... Syndrome (SS), ... (SLE), Systemic ... Kumfer @AnnKumfer #Antinuclear
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #Lupus #Erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... Syndrome (SS), ... (SLE), Systemic ... (SLE), Systemic
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... is clinically suspected ... overlap syndromes ... autoantibodies #Systemic
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
Differential Diagnosis Algorithm ... Stevens-Johnson Syndrome ... necrolysis - Systemic ... Disease • Systemic ... lupus erythematosus
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... cases • Sjögren syndrome
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... (SLE) General: ... Demyelinating syndromes ... #SLE #systemic
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Differential Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... Lupus - with Systemic ... Lupus Erythematosus ... (SLE), should have
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Demyelinating Syndrome ... RheumOnePagers) #Systemic ... #SLE #CNS #neurology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... Clinical Presentation ... Fever is the main clinical ... lupus erythematosus ... [SLE], AOSD) •
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