23 results
rheumatology differential management hematology symptoms algorithm syndrome classification druginduced erythematosus manifestations neurology oncology pathophysiology systemic acute aki anesthesia anesthesiology antiphospholipid
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... disease (10%) : SLE ... #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : • Vascular occlusion ... Splenomegaly - CTD (SLE ... Associated - SLE ... #nonpalpable #dermatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... #rheumatology #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... Erythematosus #Diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: ... Butterfly rash, Vasculitis ... erythematosus #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... such as systemic lupus ... reactions, and vaso-occlusive ... purpura: strong sign ... , and SLE) • Urinalysis
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
- Differential Diagnosis ... Rhabdomyolysis, Critical ... body-), PMR, RA, SLE ... , Vasculitis OVERLAP ... #causes #neurology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... Labs/Diagnosis: ... (e.g. systemic lupus
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... and Differential Diagnosis ... investigations depending on clinical ... context and signs ... Glomerulonephritis / Vasculits
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