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diagnosis rheumatology management ana differential autoantibodies classification patterns symptoms syndrome activation anca antibody antineutrophil antinxp2 antinxp2dm arthritis criteria dermatomyositis disease
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... #Antibodies #ANA
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease & renal ... severe disease Treatment ... #Lupus #Erythematosus
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Discoid Rash A Antinuclear ... Arthritis R Renal ... #IMDAMNSHARP #sle ... #systemic #lupus ... #erythematosus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Lupusreference #Antinuclear ... autoantibodies #Systemic ... #lupus #erythematosus
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... in drug-induced SLE ... ) • Systemic sclerosis
Renal involvement in Systemic Lupus Erythematosus (SLE) Dr. Laurent ARNAUD @Lupusreference #Renal #lupus #nephritis #SLE #Systemic #Erythematosus #SLE
in Systemic Lupus ... Erythematosus ( ... #SLE #Systemic ... #Erythematosus # ... #treatment
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies ... #Systemic #Lupus ... #Erythematosus ... autoantibodies #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Abdominal pain (20%) Renal ... #SLE #systemic ... #erythematosus # ... signs #symptoms
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... hemolysis • Renal ... Highly specific antibodies ... Classification #Criteria #SLE ... #Systemic #Lupus
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