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diagnosis rheumatology symptoms erythematosus management differential syndrome classification disease hematology oncology vasculitis activation allergy anesthesia anesthesiology autoantibodies behcet checklist chronic
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... - Arthralgia, Arthritis ... Complications #pathophysiology ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... of hip (rare), Arthritis ... Abdominal pain (20%) Renal ... #SLE #systemic ... erythematosus #signs
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Antinuclear Antibody (ANA ... cytopenias) A Arthritis ... R Renal Disease ... #IMDAMNSHARP #sle ... #systemic #lupus
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
: Pathogenesis and ... like rheumatoid arthritis ... lupus erythematosus ... (SLE) Signs / ... Sjogrens #Syndrome #Pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
the cause: • Systemic ... Lupus • Erythematosus ... (SLE) If bacterial ... the cause: • Arthritis ... Allergy #Immunology #pathophysiology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... Auto-Antibodies: - ANA ... #Systemic #Lupus ... autoantibodies #signs
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... : - ANA > ... months to years) Systemic ... : - ANA >
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Skin Findings and ... Suggestive of: Lupus ... migrans: • Target sign ... Suggestive of systemic ... gabrieltalledop #dermatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... hemolysis • Renal ... low C4, Low C3 and ... Classification #Criteria #SLE ... #Systemic #Lupus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Neuropsychiatric systemic ... APLA/LAC: • Renal ... antibodies • (-) ANA ... #Systemic #Lupus
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