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diagnosis rheumatology hematology differential erythematosus gammopathy management mgus signs ana antinuclear chronic classification cll leukemia lymphocytic significance syndrome algorithm anca
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... context of other symptoms ... (SLE), Systemic ... (SLE), Systemic
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Neurologic-Centered: (+) Systemic ... Cryoglobulinemia (-) Systemic ... Cryoglobulinemia Renal-centered ... Differential #Diagnosis #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Reactive: - Systemic ... Inflammatory • Systemic ... Lupus Erythematosus ... Lymphocytes) - Monoclonal ... #Oncology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies ... Lupusreference #SLE ... #Systemic #Lupus ... autoantibodies #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Abdominal pain (20%) Renal ... Thrombocytopenia #Lupus ... #SLE #systemic ... erythematosus #signs #symptoms
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... hemolysis • Renal ... Highly specific antibodies ... Classification #Criteria #SLE ... #Systemic #Lupus
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... to cold IgG • Lupus ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... in drug-induced SLE ... ) • Systemic sclerosis ... Antineutrophil #antibodies
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... : • Symptoms limited ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies ... #Systemic #Lupus
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Constitutional symptoms ... fludarabine) 3) Monoclonal ... antibodies (rituximab ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
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