13 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Demyelinating syndromes ... Leucopenia/lymphopenia, Thrombocytopenia ... #Lupus #SLE #systemic ... signs #symptoms #diagnosis
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... : systemic lupus ... #Differential #Comparison ... #Table #Pulmonary
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... overlap syndromes ... autoantibodies #Systemic ... #diagnosis #rheumatology ... #table #ANA
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... TTP/HUS, HELLP Syndrome ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... leukopenia, anemia, and thrombocytopenia ... #Diagnosis #Management
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus ... (SLE): ANA (anti-nuclear ... • Scleroderma (Systemic ... #Rheumatology #diagnosis ... #associations #table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... management of SLE ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
) - SLE ( ... systemic lupus erythematosus ... Haemolytic uraemic syndrome ... Henoch—Schönlein purpura, SLE ... peds #pediatrics #diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
sputum, fever, rhinitis ... , hemoptysis; +systemic ... Hypereosinophilic Syndrome ... #differential #diagnosis ... #comparison #table