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rheumatology management differential erythematosus syndrome oncology classification hematology signs criteria disease druginduced manifestations skin symptoms activation arthritis behcet chronic cll
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
the context of cutaneous ... disease (10%) : SLE ... #dermatology #semiology ... signs #lesions #diagnosis ... #clinical #manifestations
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... Clinical and Immunologic ... Criteria CLINICAL ... CUTANEOUS LUPUS
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... Rare (SSA+ for cutaneous ... months to years) Systemic ... #rheumatology #diagnosis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... Clinical Domains ... Classification #Criteria #SLE ... #Systemic #Lupus ... Erythematosus #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... #lupus #Systemic
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... Butterfly rash, Vasculitis ... #SLE #systemic ... signs #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... #Systemic #Lupus ... Erythematosus #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... aphthous ulcers, cutaneous ... lupus erythematosus ... strong sign of cutaneous ... , and SLE) • Urinalysis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
dermatomyositis, SLE ... leukocytoclastic vasculitis ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... Labs/Diagnosis: ... Henoch-Schönlein purpura) • Cutaneous ... lupus erythematosus
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