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differential rheumatology management hematology nephrology symptoms erythematosus secondary classification physicalexam workup clinical comparison hairloss manifestations msk oncology pathophysiology primary vasculitis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Photosensitivity, Alopecia ... Workup: - ANA ... #lupus #Systemic
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Diagnosis Framework ... , Loose anagen syndrome ... Examination: • Signs ... Vitamin D levels Systemic ... #dermatology #Hairloss
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Algorithm DIFFUSE ... • Loose anagen syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
- Differential Diagnosis ... Algorithm Erosions ... necrolysis - Systemic ... lupus erythematosus ... #Algorithm #causes
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... • Red plaques ... hair follicles -> causes ... pathophysiology #diagnosis ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Myopathy (Also caused ... pathophysiology #signs ... #symptoms #diagnosis
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... - NON-SCARRING ALOPECIA ... SEROSITIS - RENAL - NEUROLOGIC ... #Rheumatology #SLE
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
central nervous system ... Inflammatory causes ... • Systemic lupus ... #neurology #inflammatory ... #differential #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... #SLE #CNS #neurology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
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