13 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 1 • Clinical Manifestations ... • Laboratory Manifestations ... Positive in 60-80% of cases ... #lupus #Systemic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Demyelinating Syndrome ... autoantibodies that will cause ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin manifestations ... block • Sjogren syndrome ... #Lupus #Erythematosus ... #rheumatology #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... Discontinuation of causal ... months to years) Systemic ... Usual therapeutic management ... rheumatology #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... main clinical manifestation ... lupus erythematosus ... [SLE], AOSD) • ... #Diagnosis #Management
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... involvement: Intractable nausea ... autoimmune disorders (Systemic ... lupus erythematosus ... #Optica #NMO #Manifestations
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Abnormality • SLE ... • Nephrotic syndrome ... #Secondary #dermatology ... Diagnosis #Algorithm #causes
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Disease (IgG4-RD ... Arthritis (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
entire breathing system ... be diagnostic – see ... overload / TURP syndrome ... ) • Medical causes ... Checklist #Diagnosis #Management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... Musculoskeletal system ... Causes: - Idiopathic ... - Lupus - Leukemia ... #diagnosis #dermatology