13 results
Renal involvement in Systemic Lupus Erythematosus (SLE)

Dr. Laurent ARNAUD @Lupusreference

#Renal #lupus #nephritis #SLE #Systemic #Erythematosus #SLE
Renal involvement ... in Systemic Lupus ... #lupus #nephritis ... #SLE #Systemic ... #management #treatment
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
at least 50% Renal ... Drugs • Emboli Systemic ... IgA, post-strep, lupus ... Interstitial Nephritis ... Sjögren) Post-Renal
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
, Acute cutaneous ... hemolysis • Renal ... nephritis, Class ... Classification #Criteria #SLE ... #Systemic #Lupus
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... thromboembolism, renal ... Secondary GNs: Due to systemic ... Post-infectious GN, Lupus ... Interstitial Nephritis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and a high ... Classification: • Acute ... APLA/LAC: • Renal ... #Systemic #Lupus
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... Severe disease- high ... #Lupus #Erythematosus ... #rheumatology #management
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... vasoconstriction-hemodynamically mediated - Systemic ... - Glomerular (red ... appropriate) #Acute ... Kidney #Injury #AKI
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Abnormality • SLE ... discoloration) • Chronic renal ... discoloration) • Nephrotic ... #Secondary #dermatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Attempt if high ... Renal Failure ... coagulopathy, RRT ... APML #diagnosis #management ... #hematology #oncology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Epidemiology 1) High ... the lymphatic system ... , and possibly renal ... skin (16-32%): lupus