11 results
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
at least 50% Renal ... Drugs • Emboli Systemic ... IgA, post-strep, lupus ... Interstitial Nephritis ... , sarcoid, Sjögren
Renal involvement in Systemic Lupus Erythematosus (SLE)

Dr. Laurent ARNAUD @Lupusreference

#Renal #lupus #nephritis #SLE #Systemic #Erythematosus #SLE
Renal involvement ... in Systemic Lupus ... #lupus #nephritis ... #SLE #Systemic ... #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute ... dermatomyositis, Sjogren ... APLA/LAC: • Renal ... #Systemic #Lupus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
, Acute cutaneous ... hemolysis • Renal ... nephritis, Class ... Classification #Criteria #SLE ... #Systemic #Lupus
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... heart block • Sjogren ... #Lupus #Erythematosus ... #rheumatology #management
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... thromboembolism, renal ... Secondary GNs: Due to systemic ... Post-infectious GN, Lupus ... Interstitial Nephritis
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... vasoconstriction-hemodynamically mediated - Systemic ... - Glomerular (red ... appropriate) #Acute ... Kidney #Injury #AKI
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Abnormality • SLE ... discoloration) • Chronic renal ... discoloration) • Nephrotic ... #Secondary #dermatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... cirrhosis: 3%-20% Renal ... • Interstitial nephritis ... Distal (Type I) renal ... Rheumatology #Diagnosis #Management
Facial Swelling - Differential Diagnosis Framework for Facial Edema

Infectious:
	• Dental abscess
	• Ludwig's angina
	• Vincent's angina
	• Cellulitis
	•
Autoimmune: • SLE ... Still's disease • Sjogren's ... Preeclampsia Dermatologic ... Subcutaneous emphysema Renal ... : • Nephrotic