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differential causes macrocytic management thrombocytopenia aplastic disorders leukemia myelodysplastic pancytopenia antiphospholipid cancer chronic classification cll deficiency dyspnea elevatedmcv emergencies evaluation
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... vs Hypocellular MDS ... Expectation • Rx Algorithm ... #diagnosis #oncology ... #hematololgy
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Deficiency • MDS ... #Macrocytic #Anemia ... #differential #diagnosis ... #algorithm #hematology ... #workup
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... the peripheral blood ... hemolytic uremic syndrome ... thrombocytopenia, Hematology ... 2012, p 193 #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... hemolysis, deficiency anemia ... #Algorithm #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... (ST-HUS) - ... macroangiopathic hemolytic anemia ... • Catastrophic APLS ... #hematology #hemolysis
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Algorithm Consumption ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Algorithm Consumption ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Algorithm #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... SLE • CLL • APLA ... Non-lmmune: • HELLP Syndrome ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... cytopenias (usually anemia ... #MDS #Diagnosis ... Management #treatment #hematology ... #oncology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Algorithm Labs ... TSAT, sTfR • Blood ... Gastrectomy, WHDA syndrome ... Matthew Ho, MD ... #hematology
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