23 results
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... intravascular coagulation ... MAHA: TTP, HUS, DIC ... Diagnosis #clots #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- DIC/TTP/HUS ... Defects: • DIC ... Purpura Fulminans (DIC ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... Anticoagulant Medications ... Post-partum • Acute DIC ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Severe Liver Disease ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
For most indications ... hemorrhage, while under-coagulation ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... schistocytes, DIC ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... schistocytes, DIC ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... family history - Medications ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... #Workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... • Reaction to Medications ... Diagnosis #Algorithm #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation ... (DIC) - HELLP ... Extravascular #Causes ... differential #diagnosis #hematology