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management differential lupus sle systemic comparison antibodies antinuclear dermatology hematology summary autoantibodies classification medications syndrome vasculitis algorithm diseases druginduced hivaids
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... (MCTD), Drug-induced ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Systemic lupus erythematosus ... (MCTD), Drug-induced ... Systemic lupus erythematosus ... #patterns #rheumatology ... #diagnosis #differential
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
angiitis induced by drugs ... systemic lupus erythematosus ... Vasculitis #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... Treatment: • ... #SLE #Summary #diagnosis ... #rheumatology #
Shock and Vasoactive Drugs 1) Determine type and etiology of shock • Distributive: Sepsis, Anaphylaxis, Neurogenic
Failure, Valvular Disease ... pharmacology ... #pharmacology # ... inopressors #diagnosis ... management #comparison #table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... extremities Drug ... • Antihistone: Drug ... #Diagnosis #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... ANA - Non-specific ... Anti-histone - Drug-induced ... #diagnosis #table ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... : Drug-induced lupus ... sclerosis, Still's disease ... #differential #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... life-threatening • Treatment ... Evolution: Chronic disease ... #Summary #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Systemic lupus erythematosus ... Anti-histone (in drug-induced ... Jcortesizaguirr #ANA ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
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