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diagnosis management erythematosus differential ana syndrome antibodies symptoms autoantibodies comparison patterns summary workup activation anca antibody antineutrophil arthritis associations behcet
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... tissue disease ... (SLE), Systemic ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Discoid Rash A Antinuclear ... Pleuritis) H Hematologic ... #IMDAMNSHARP #sle ... #systemic #lupus ... erythematosus #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Treatment: • ... #Lupus #Erythematosus ... diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Systemic ... : Lupus (SLE), Systemic ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... #diagnosis #rheumatology ... #table #ANA
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... rheumatoid arthritis SLE ... : systemic lupus ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... pain (20%) Renal disease ... #SLE #systemic ... erythematosus #signs ... symptoms #diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... antibodies #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... life-threatening • Treatment ... Evolution: Chronic disease ... #lupus #Systemic ... Management #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology #
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