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diagnosis hematology anemia algorithm hemolysis causes extravascular intravascular management agglutinin antibody classification cold disease hodgkins lymphoma oncology pathophysiology platelets rheumatology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Abnormal peripheral smear ... : • Autoimmune ... (AIHAs) • Alloimmune ... #Anemias #Differential
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Differential Diagnosis ... #Hemolytic #Anemia ... #AIHA #Differential
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... or negative - Smear ... C3 positive - Smear ... #Autoimmune #Hemolytic
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... 1) DIAGNOSE AIHA ... C3d • Blood smear ... : Differential → ... #Hemolytic #Anemia
Anemia - Hemolysis Diagnostic Algorithm Autoimmune hemolytic anemia Microangiopathic hemolytic anemia Probable thalassemia Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis ... Diagnostic Algorithm Autoimmune ... hemolytic anemia ... hematology #diagnosis #differential ... #workup
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Autoimmune Hemolytic ... Anemia (AIHA) ... #Hemolytic #Anemia ... #AIHA #Diagnosis ... #Differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... (AIHA) "Warm" ( ... idiopathic) - Autoimmune ... (AIHA)"Cold" (usually ... Extravascular #Causes #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... • Cold AIHA ... • Alloimmune ... anemia • ... Extravascular #Differential
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... - Differential ... Peripheral blood smear ... idiopathic, malignancy, autoimmune ... #Anemia #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... : Warm AIHA, Cold ... Defects: Sickle cell anemia ... Peripheral Blood Smear
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