5325 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• TMA’s (HUS/TTP ... Schistocytes - MAHA: TTP ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP ... HELLP Syndrome • TTP ... Diagnosis #Algorithm #Causes
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
needle + 3-way tap ... Plan definitive management ... • Identify tip ... small volume may cause ... Checklist #Diagnosis #Management
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic Purpura (TTP ... Diagnosis of TTP ... • Distinguish TTP ... Treatment of TTP ... Thrombocytopenic #Purpura #management
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... MALIGNANCY: - TMA: TTP ... HIT - MAHA: TTP
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Microangiopathy: DIC, TTP ... Antibody-mediated: ITP
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... Thrombocytopenia: ITP ... • Secondary Causes ... disease - DIC/TTP ... Defects: • DIC, TTP
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... TMA is due to TTP ... compliment-mediated TTP ... TTP is only TMA ... suggests against TTP
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP ... implications : TTP ... confirmatory testing for TTP ... thrombocytopenic #purpura #TTP
Management of Immune Thrombocytopenia (ITP) . 

#Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
Management of Immune ... Thrombocytopenia (ITP ... Thrombocytopenia #ITP ... #Management #Hematology