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Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP ... • Nephrotic Syndrome ... considered in all cases ... coagulation and other causes ... Venous #Arterial #pathophysiology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS • ... Diagnosis #Algorithm #Causes
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Microangiopathy: DIC, TTP ... Antibody-mediated: ITP ... antiphospholipid syndrome
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Thrombocytopenia: ITP ... disease - DIC/TTP ... Kasabach-Merritt syndrome ... Defects: • DIC, TTP ... Gardner-Diamond syndrome
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
and Pregnancy - TTP ... /HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... child * Severe cases ... plasma exchange 2) TTP
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Sarcoidosis or Lofgren's syndrome ... Nodosum #Mnemonic #Causes
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... MALIGNANCY: - TMA: TTP ... HIT - MAHA: TTP
Torsades de Pointes (TdP): Pathogenesis and Clinical Findings Polymorphic ventricular tachycardia initiated by PVC in the setting
Torsades de Pointes (TdP ... Torsades #dePointes #TdP ... #Diagnosis #pathophysiology ... #cardiology #causes
Hyperthermic Syndromes - This table summarizes the similarities and differences between some toxicologic causes of hyperthermic
Hyperthermic Syndromes ... some toxicologic causes ... of hyperthermic syndromes ... • Serotonin syndrome ... #Hyperthermic #Syndromes
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... TMA is due to TTP ... compliment-mediated TTP ... TTP is only TMA ... suggests against TTP
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