24 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... Lysis -> Release ... urine pH) • Hypocalcemia
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... cell lysis → Release ... #TLS #Pathophysiology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH
LOW PTH - Hypoparathyroid
 - Congenital (Pediatric)
Hypocalcemia - Differential ... Tumor lysis syndrome ... laxatives) #Hypocalcemia ... Algorithm #PTH #endocrinology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperphosphatemia, #hypocalcemia ... acutekidneyinjury #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... Lysis Syndrome: ... : Lysis of tumor ... #Lysis #Syndrome ... TLS #diagnosis #management
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... treatment • Hypocalcemia ... #TumorLysis #Syndrome ... TLS #diagnosis #management
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Cancer Related • Hypercalcemia ... nephropathy • Solid tumors ... Capillary leak syndrome ... Interleukin-2) • Tumor ... lysis syndrome
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... lysis kbs every ... #Lysis #Syndrome ... #diagnosis #management
Adrenal Incidentalomas: Hormone Evaluation
 • Zona Glomerulosa: Primary Hyperaldosteronism?
    - Aldosterone and renin
Aldosterone and renin if hypokalemia ... Fasciculata: Cushing Syndrome ... for those with tumor ... mendesthiagob #Adrenal #Tumors ... Diagnosis #workup #endocrinology
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
Hypocalcemia - Diagnosis ... and Management ... - DiGeorge Syndrome ... #Diagnosis #Management ... #endocrinology