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Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... , Mechanism of Action ... Tolvaptan #Diuretics ... Pharmacology #summary #table ... #nephrology
Unmeasured Anions Associated with an Elevated Anion Gap and Metabolic Acidosis

#Unmeasured #Anions #Gap #Metabolic #Acidosis #Diagnosis
with an Elevated Anion ... Gap and Metabolic ... Acidosis #Diagnosis #Nephrology ... #Table #Differential ... #Causes
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Gap and Non-anion ... Causes of High-anion ... of Non-anion Gap ... #nephrology
Metabolic and Respiratory Acidosis and Alkalosis - Diagnostic Algorithm

Anion gap - MUDPILES: 
 - Methanol (formic
Alkalosis - Diagnostic Algorithm ... Anion gap - ... gap - HARDASS: ... Respiratory #Metabolic #Algorithm ... Recommended Text: Nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... , nasogastric suction ... , Osmotic diuresis ... #Hypokalemia #Causes ... differential #diagnosis #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... Renal losses, Diuretic ... Ketonuria, Osmotic diuresis ... #Causes #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Kidney stones caused ... the Nonspecific Cation ... #Nephrology #Pharmacology ... #Medications #Table
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... organic acids and bases ... acid and most diuretics ... tubule (DCT) - Active ... Pathophysiology #Tubules #Table
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... loss: Nasogastric suction ... • Drugs: Loop diuretics ... Hypomagnesemia #Causes ... differential #diagnosis #nephrology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... - Nasogastric suction ... Saline or osmotic diuresis ... Drugs: - Loop diuretics ... Hypomagnesemia #Causes