Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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18 results
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 β€’ Membrane
 β€’ Internal
    - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Diagnosis Inherited ... #Diagnosis #Causes ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 β€’ Anemia: macrocytic > normocytic, ↑ reticulocytes
 β€’
Anemia 1) DIAGNOSE ... β€’ Blood smear: Differential ... 2) LOOK FOR a cause ... #management #treatment ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 β€’ Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 β€’ Enzyme deficiencies ex. G6PD, pyruvate kinase 
 β€’ Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... #Anemia #Differential ... #Diagnosis #causes ... classification #hematology
Etiologies of Folate Deficiency
 β€’ Decreased dietary intake - uncommon in this era
 β€’ Increased requirements
Etiologies of Folate ... pregnant have hemolytic ... that can cause ... deficiency #FolicAcid #differential ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 β€’ Acute infection
 β€’ Solid organ
- Differential ... Diagnosis Secondary ... iron deficiency, hemolysis ... #Diagnosis #Causes ... #hematology #secondary
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... Diagnosis Framework ... : B12, copper, folate ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
, Vitamin B12, Folate ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Vitamin B12 or Folate ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 β€’ Iron deficiency
Diagnostic Framework ... B12 deficiency, Folate ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology