Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Drugs Commonly Implicated as Triggers of Drug Induced Thrombocytopenia
#Diagnosis #Hematology #Thrombocytopenia #Differential #DrugInduced #Medications
Thrombocytopenia #Diagnosis ... #Hematology #Thrombocytopenia ... #Differential #DrugInduced ... #Medications
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 β€’ AST/ALT elevation
Liver Enzymes (LFTs ... Cholestatic Liver Injury ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis ... #differential #hepatology
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Thrombocytopenia The diagnosis ... are initially diagnosed ... #Diagnosis #Hematology ... #Differential #DrugInduced ... #Medications #Causes
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Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 β€’ NAFLD
 β€’ Cirrhosis
 β€’
Function Tests (LFTs ... - Differential Diagnosis ... Drug-induced liver injury ... Function #Tests #LFTs ... #hepatology #transaminitis
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs ... Hepatocellular injury ... #FunctionTest #LFTs ... Transaminitis #diagnosis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury β†’ liver test abnormalities without evidence of liver
- Differential Diagnosis ... Differential Diagnosis ... , HSV, VZV β€’ Medications ... #hepatology #algorithm ... Transaminitis #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 β€’ Intrinsic - predictable, dose dependent
Diagnosis and Management ... dose dependent injury ... Chronic - ongoing ↑ LFTs ... #differential #Diagnosis ... gastroenterology #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... Patterns #Liver #Injury ... #hepatology #LFTs ... #differential #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 β€’ Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential Diagnosis ... Toxic: Alcohol, Medication ... #Differential #Diagnosis ... Acute #algorithm #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Function Tests (LFTs ... hepatocellular injury ... Function #Tests #LFTs ... Interpretation #diagnosis ... #hepatology