Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
Antimalarial drugs ... widening #ECG #EKG #Pharmacology ... #Medications #Toxicology ... #Diagnosis #Differential ... #Drugs #Classes
Potassium Channel Blockers - Medications
1. Cardiovascular Drugs
2. Psychiatric drugs
3. Other drugs
4. Synthetic opioids: Levomethadyl 
5. Opium
Psychiatric drugs ... Other drugs 4. ... #Medications #Differential ... #Diagnosis #Pharmacology ... #Toxicology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Drugs Implicated in Hemolytic Anemia
 β€’ Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... Anemia β€’ Hapten (Drug ... Omeprazole, Sulfa drugs ... Hemolytic #Anemia #differential ... #diagnosis #pharmacology
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 β€’ Distributive: Sepsis, Anaphylaxis, Neurogenic
and Vasoactive Drugs ... pharmacology ... #pharmacology # ... inopressors #diagnosis ... #management #comparison
Drugs that Cause Fever
Most commonly:
Amphotericin B, Antihistamines, Asparaginase, Barbiturates, Bleomycin sulfate, Methyldopa, Penicillins, Phenytoin sodium, Procainamide,
Drugs that Cause ... hydrochloride #Drug ... Fever #causes #differential ... #diagnosis #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 β€’ Direct renin inhibitor (Aliskiren)
 β€’ Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
Common causes: - Drug ... CD3-CD4+ T cells ... hypereosinophilia #HE #Differential ... #Diagnosis #Causes
Vancomycin Associated Acute Kidney Injury

 β€’ Drug induced acute kidney injury is generally defined as a
Kidney Injury β€’ Drug ... 24-72 hours of drug ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis ... #management #nephrology
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Kidney Injury - Differential ... urinalysis, labs - Management ... renal biopsy - Management ... Avoiding nephrotoxic drugs ... #Injury #AKI #Differential