The Calgary Guide to Understanding Disease @TheCalgaryGuide
551.0K 395 156
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
Contributor Ranks
Latest Searches
26 results
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
maladaptive beliefs and anxiety ... Dysregulation of anxiety ... reduce obsessional anxiety ... PersonalityDisorder #Diagnosis #Psychiatry
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Third Generation Antipsychotics ... Antidepressant Effects #AntiPsychotics ... pharmacology #diagnosis #psychiatry
Pathogenesis of Anxiety Disorders

Anxiety Disorders: A maladaptive emotional state causing fear,
worry, and excessive stress, characterized by:
Pathogenesis of Anxiety ... Disorders Anxiety ... Predisposition to anxiety ... acid (GABA) #Anxiety ... Pathophysiology #diagnosis #psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... partum onset) - Anxiety ... Signs #Symptoms #Psychiatry
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... symptoms #signs #psychiatry
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Second Generation Antipsychotics ... Mechanism unknown #AntiPsychotics ... pharmacology #diagnosis #psychiatry
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
anhedonia • Social Anxiety ... reference - Anxiety ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
, seizure, and anxiety ... Signs #Symptoms #Psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
- Incr guilt, anxiety ... Signs #Symptoms #Psychiatry