The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... pathophysiology #signs ... #symptoms #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... Fractures #msk #diagnosis ... pathophysiology #signs ... #symptoms #orthopedics
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... the etiology Signs ... endocrinology #symptoms #signs ... #diagnosis
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk #orthopedics
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... chromosome 21) Signs ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
#Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... erythematosus (SLE) Signs ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
sensory • Before diagnosis ... intervertebral disc disease ... pathophysiology #differential ... #diagnosis #signs
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... 40% of patients diagnosed ... history of the disease ... Signs of immunodeficiency ... humoral immunity Signs
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... pathophysiology #diagnosis ... #signs #symptoms