The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis signs behavioraldisorder mooddisorders riskfactors sad affectivedisorder alcoholusedisorder anorexianervosa aseptic bipolar bulimianervosa complications criteria diabetes diabeticketoacidosis disorder dysfunction erectile etoh
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Major Depressive ... partum onset) - Anxiety ... features) #MDD #MajorDepressiveDisorder ... #Diagnosis #Pathophysiology ... #Psychiatry
Major Depressive Disorder: Complications • Recurrent Depressive Episodes • Early parenthood • Social isolation and interpersonal
Major Depressive ... dependence • Anxiety ... birth weight #MajorDepressiveDisorder ... Complications #Pathophysiology ... #Psychiatry
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
startle reflex • Anxiety ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
maintain this state Depressive ... - Incr guilt, anxiety ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
• Withdrawal symptoms ... , seizure, and anxiety ... AlcoholUseDisorder #EtOH #Pathophysiology ... Diagnosis #Signs #Symptoms ... #Psychiatry
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... Signs/Symptoms/Complications ... #pathophysiology ... #endocrinology
Schizophrenia: Pathogenesis and Symptoms Increased dopaminergic transmission in mesolimbic projection -> Dopaminergic neurons here project into the limbic
Pathogenesis and Symptoms ... cause the Positive Symptoms ... Diminished emotional expression ... Schizophrenia #pathophysiology ... #signs #psychiatry
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
pathway -> Incr gene expression ... lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... #pathophysiology
Pediatric Parasomnias and Nightmares: Pathogenesis and clinical findings Parasomnias - Micro-arousal episodes during SWS -> Intense activation of
Fearful facial expression ... system -> • Fear/anxiety ... Pediatrics #Peds #pathophysiology ... #symptoms #pharmacology
Seasonal Affective Disorder: Pathogenesis and clinical findings Symptoms (included in the DSM-V) - Two Major Depressive episodes
clinical findings Symptoms ... season at work) Symptoms ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
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