The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #MSK #Musculoskeletal ... #Complications ... signs #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... distension #Systemic ... Erythematosus #SLE ... Gastrointestinal #Complications ... signs #symptoms #diagnosis
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Clinical Features and Complications ... Gustilo-Anderson Classification ... Open #Fractures #Diagnosis ... #Complications ... #MSK #Orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Classification of ... Clinical Features and Complications ... PelvicRing #Fractures #Classification ... #Orthopedics #MSK ... #diagnosis #complications
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... arthritis (RA) or systemic ... erythematosus (SLE ... Pathophysiology #Diagnosis
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings

Predisposing Factors:
 - Immunocompromised, Diabetes,
 - Elderly, Female
usual defense system ... lower tract: As a complication ... bacteriuria or cystitis (see
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Signs/Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
complexes • Ex: Systemic ... Reactions #Types #Classification ... #Diagnosis #Definitions
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Signs/Symptoms/Complications ... TendonRupture #diagnosis ... pathophysiology #msk
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Phenomenon #Lupus #SLE ... pathophysiology #diagnosis ... signs #symptoms #complications