The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... pathophysiology #symptoms #signs
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... #PelvicRing #Fractures ... Classification #Grades #Grading ... #Orthopedics #MSK ... #diagnosis #complications
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... onto lateral hip Signs ... • Non-union of fracture ... #msk #diagnosis ... pathophysiology #signs
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
interarticularis stress fracture ... XR — scotty dog sign ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology ... #signs #symptoms
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
pain • Palpable grinding ... pathophysiology #diagnosis ... #signs #symptoms ... #msk
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, humeral head fracture ... pathophysiology #diagnosis ... #symptoms #signs ... #stages #staging ... #msk
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Oscillation between mood states ... distractibility - racing ... maintain this state ... MoodDisorders #Diagnosis ... Pathophysiology #Signs
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Greater Trochanter Fracture ... causes #symptoms #signs ... #diagnosis #msk
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Inflammatory Stage ... site Soft Callus Stage ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology #diagnosis
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
bone formation MSK ... -> Pathologic fractures ... Nephrolithiasis (Kidney Stones ... pathophysiology #diagnosis ... #signs #symptoms