The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Stress Fracture: ... subthreshold mechanical loading ... from continued loading ... StressFractures #msk #orthopedics ... pathophysiology #symptoms
Clavicular Fracture: Pathogenesis and clinical findings

Group I (69%) - Middle third (mid-shaft)
Group II (29%) - Distal
Clavicular Fracture ... and the site of fracture ... other injuries in all ... #Clavicular #Fracture ... #Grading #Diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... lateral hip Signs/Symptoms ... #msk #diagnosis ... pathophysiology #signs #symptoms ... #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... Grade 2 - Rami fracture ... Classification #Grades #Grading ... #Orthopedics #MSK ... #diagnosis #complications
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
Acute Compartment ... bleeding tendency/fracture ... compartment pressure #Acute ... CompartmentSyndrome #ACS ... pathophysiology #orthopedics
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
- Alcohol craving ... • Withdrawal symptoms ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Psychiatry
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Block action of ACh ... Extrapyramidal Symptoms ... bradykinesia/akinesia • Acute ... #pharmacology #diagnosis ... #psychiatry
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... etiology Signs/Symptoms ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk #orthopedics
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
distractibility - racing ... MoodDisorders #Diagnosis ... Pathophysiology #Signs #Symptoms ... #Psychiatry
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... #Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics