The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... reaction, Myasthenia Gravis ... , Graves' Disease ... Classification #Diagnosis
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
cyclist) - APC Grade ... 2.5cm - APC Grade ... auto) - LC Grade ... #Grading #Orthopedics ... #MSK #diagnosis
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
#Sports #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... pathophysiology #immunology #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... symptoms #signs #diagnosis
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... leading to an allergic ... An allergic reaction ... #Allergic #Reactions ... Classification #Diagnosis
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Open #Fractures #Diagnosis ... Complications #MSK #Orthopedics
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
#Dislocation #Diagnosis ... symptoms #msk #orthopedics
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Fractures #msk #diagnosis ... signs #symptoms #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
TendonRupture #diagnosis ... pathophysiology #msk #orthopedics