The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
- Incr guilt, anxiety ... Bipolar #Disorder #MoodDisorders ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
partum onset) - Anxiety ... MajorDepressiveDisorder #Depression #MoodDisorders ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
carrying anti-anxiety ... #BehavioralDisorder ... #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
, seizure, and anxiety ... AlcoholUseDisorder #EtOH #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Psychiatry
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
(SAD) - Pathophysiology ... SocialAnxiety #BehavioralDisorder ... #SAD #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry #criteria
Seasonal Affective Disorder: Pathogenesis and clinical findings

Symptoms (included in the DSM-V) - Two Major Depressive episodes
AffectiveDisorder #MoodDisorders ... #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
develop mood and anxiety ... OppositionalDefiant #ODD #BehavioralDisorder ... #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry #criteria
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
Temperament: childhood anxiety ... AnorexiaNervosa #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry