The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis msk signs symptoms geriatrics peds alzheimersdisease anorexianervosa classification fecal femoralhead genetics incontinence lewybody lowanklesprain ophthalmology pelvicring praderwilli prematurity psychiatry
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... and Complications ... #Grading #Orthopedics ... MSK #diagnosis #complications ... #pathophysiology
Stress Fracture: Pathogenesis and clinical findings Abnormal biomechanics, Repetitive impact activities => Repetitive subthreshold mechanical loading => Bone strain =>
Stress Fracture: ... subthreshold mechanical loading ... from continued loading ... StressFractures #msk #orthopedics ... #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms/Complications ... Incr Skeletal fractures ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Lewy Body Dementia: Pathogenesis and Clinical Findings Lewy Body Dementia is a sub-category of major or mild
Lewy Body Dementia ... Findings Lewy Body Dementia ... Dementia should ... #pathophysiology ... #geriatrics #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Signs/Symptoms/Complications ... • Non-union of fracture ... msk #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Fecal Incontinence - Pathogenesis and Complications Continence mechanisms are impaired • Local neuronal damage • External and
Pathogenesis and Complications ... (e.g. stroke, dementia ... #Incontinence #geriatrics ... #pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Signs / Symptoms / Complications ... AlzheimersDisease #Dementia ... #pathophysiology ... #geriatrics #diagnosis
Retinopathy of Prematurity: Pathogenesis and clinical findings Increased metabolic demand of growing eye -> Excessive VEGF production ->
metabolic demand of growing ... -> Neovascular complications ... branching of vessels leading ... Prematurity #peds #pediatrics ... #pathophysiology
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
Anorexia Nervosa: Complications ... increased risk of fracture ... Death - Cardiac complications ... highest mortality rates ... #pathophysiology
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