The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
and Complications ... Anterior Sl diastasis ... Grades #Grading #Orthopedics ... MSK #diagnosis #complications ... #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Erythematosus #SLE ... Gastrointestinal #Complications ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Signs/Symptoms/Complications ... • Non-union of fracture ... msk #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... pseudo-widening in Sl ... column) • Late complication ... bamboo spine) -> Fracture ... AnkylosingSpondylitis #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... Phenomenon #Lupus #SLE ... Manifestations #pathophysiology ... signs #symptoms #complications
Acute Compartment Syndrome
 • Crush injuries, burns, circumferential constriction to limbs (each containing facially divided muscle
bleeding tendency/fracture ... allow fluid to disperse ... CompartmentSyndrome #ACS #pathophysiology ... #orthopedics
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... Signs/Symptoms/Complications ... #Kawasaki #Disease ... Criteria #Diagnosis #Pathophysiology ... Signs #Symptoms #Vasculitis
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
/ Behavioural Features ... Problems and Facial Features ... erosion and gum disease ... Symptoms related to complications ... BulimiaNervosa #pathophysiology
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... Complications ... -> Pathologic fractures ... PagetsDisease #pathophysiology ... signs #symptoms #complications