The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs msk complications psychiatry acute endocrinology ophthalmology sle ankylosingspondylitis arteritis bulimianervosa chondrocalcinosis compartmentsyndrome cppd erythematosus extraarticular inhibitors manifestations orthopedics
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... - Budd Chiari Syndrome ... Complications #pathophysiology ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... RA) or systemic lupus ... (SLE) Signs / Symptoms ... #Pathophysiology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... palpation - Vasculitic ... Temporal #Arteritis #Pathophysiology ... Diagnosis #Signs #Symptoms ... #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Complications #pathophysiology ... #signs #symptoms
Osteoporosis: Pathogenesis and risk factors • Age > 30 (post-peak bone mass) • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... #Osteoporosis #pathophysiology ... #signs #symptoms
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
Patellofemoral Syndrome ... with possible symptoms ... Patellofemoral #Syndrome ... #pathophysiology ... diagnosis #signs #symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... nephrotic/nephritic syndrome ... #HSP #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology ... Diagnosis #Signs #Symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... chromosome 21) Signs / Symptoms ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
paresthetica • Symptoms ... 3-6 months of symptom ... intervertebral disc disease ... mass Sensory Symptoms ... MeralgiaParesthetica #MSK #pathophysiology
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