The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... Gastrointestinal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Clinical findings and Complications ... Signs/Symptoms ... Temporal #Arteritis #Complications ... #Signs #Symptoms ... #diagnosis #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Systemic #Lupus #Erythematosus ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... Signs / Symptoms ... / Complications ... pathophysiology #immunology #diagnosis ... #signs #symptoms
Complications of Measles: Pathogenesis and Clinical Findings
 • ADEM -> Fever, headache, neck stiffness, BBD, mental
Complications of ... infections #Measles #Complications ... #diagnosis #signs ... #symptoms #pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
systemic lupus erythematosus ... (SLE) Signs / ... Symptoms: - Lymphocyte ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Otitis Media: Complications ... becomes more severe Signs ... /Symptoms/Complications ... pathophysiology #symptoms ... #signs #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... Fractures #msk #diagnosis ... pathophysiology #signs ... #symptoms #orthopedics
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs ... / Symptoms / Complications ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms