The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
/Symptoms/Complications ... weight-bear • Arthritic ... #msk #diagnosis ... #pathophysiology ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... #MSK #Musculoskeletal ... #Complications ... #pathophysiology ... #signs #symptoms
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
and Complications ... Anterior Sl diastasis ... #Orthopedics #MSK ... #diagnosis #complications ... #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms ... /Complications: ... Incr Skeletal fractures ... #genetics #pathophysiology ... #peds #pediatrics
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
- Budd Chiari Syndrome ... Erythematosus #SLE ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... erythematosus (SLE ... ) Signs / Symptoms ... #Pathophysiology ... #Diagnosis #Signs
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... / Symptoms / Complications ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
pseudo-widening in Sl ... column) • Late complication ... bamboo spine) -> Fracture ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
of the Hip • Arthritis ... Greater Trochanter Fracture ... Trendelenburg #Gait #pathophysiology ... causes #symptoms #signs ... #diagnosis #msk
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
resolve by 72 hours Complications ... seizures, abscess (see ... #OtitisMedia #pathophysiology ... diagnosis #symptoms #signs ... #peds #pediatrics