The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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symptoms psychiatry behavioraldisorder gh acute adhd attentiondeficithyperactivedisorder cecs chronicexertional compartmentsyndrome complications conduct depression disease endocin excess feedbackloop gravesdisease kawasaki majordepressivedisorder
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
fraction • HTN #GrowthHormone ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
auto-reactive B and CD ... RheumaticFever #pathophysiology ... #diagnosis #signs
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs ... #diagnosis
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... MoodDisorders #Diagnosis ... #Pathophysiology ... #Signs #Symptoms
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... hands & feet Signs ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
Conduct Disorder (CD): Pathogenesis and clinical findings - Must have >3 symptoms present in the past
>18 years old, criteria ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry ... #criteria
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
Syndrome (CECS) • Diagnosis ... • Diagnostic ... criteria for CECS ... CompartmentSyndrome #CECS #pathophysiology ... #diagnosis #signs
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Toxicity Criteria ... make a clinical diagnosis ... Serotonin #Syndrome #Pathophysiology ... #Psychiatry #Diagnosis ... #Signs #Symptoms
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