The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis behavioraldisorder sideeffects growthhormone pharmacology pituitary serotonin adhd attentiondeficithyperactivedisorder cd conduct depression excess feedbackloop glftap keratoconus macroadenoma majordepressivedisorder masseffects mdd
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... #Pathophysiology ... #SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... #Pathophysiology ... #SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Decr Protease inhibitors ... / Symptoms / Complications ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
have either 26 symptoms ... 2 settings - Symptoms ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
Conduct Disorder (CD): Pathogenesis and clinical findings - Must have >3 symptoms present in the past
- Must have >3 symptoms ... >18 years old, criteria ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings - Must have >4 symptoms for >6 months,
- Must have >4 symptoms ... a sibling - Symptoms ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
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