The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology complications sle erythematosus systemic avascularnecrosis caudaequina cecs chronicexertional compartmentsyndrome extraarticular femoralhead fractures gait gastrointestinal henochscholeinpurpura iga manifestations mucocutaneous musculoskeletal
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... - Budd Chiari Syndrome ... pathophysiology #signs ... #symptoms #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Signs/Symptoms ... weight-bear • Arthritic ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
• Arthritis ... • Congenital hip ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... RA) or systemic lupus ... / Symptoms: - ... Pathophysiology #Diagnosis ... #Signs #Symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
nephrotic/nephritic syndrome ... Arthralgia's (common), arthritis ... and ankles) #HSP ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... inflammation tends to cause ... pathophysiology #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Takayasu’s Arteritis: Pathogenesis and clinical findings - Fatigue, weight loss, low grade fever, arthralgias - Incr
Takayasu’s Arteritis ... Acute Coronary Syndrome ... #Takayasus #Arteritis ... #Vasculitis #Diagnosis ... #Signs #Symptoms
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