The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs symptoms fractures grades grading sle achilles acute classification comparison degenerative disruptors erythematosus femoralhead fracture inflammatory injury jointdisease jointpain lowanklesprain
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... #pathophysiology ... signs #symptoms #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
• Avulsion or shearing ... Signs/Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... with keratotic scaling ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Low Ankle Sprain: Pathomechanics and Clinical Findings Grading Ligament Sprains l: Minimal ligament disruption, mild swelling & tenderness,
ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... #Grades #Diagnosis ... #pathophysiology
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
Signs/Symptoms/Complications ... TendonRupture #diagnosis ... signs #symptoms #pathophysiology ... #msk #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... Grades #Grading #Orthopedics ... #MSK #diagnosis ... #complications ... #pathophysiology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Rheumatoid arthritis, Lupus ... Larger, weight-bearing ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis ... #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Injury #Syndromes #diagnosis ... #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology ... #diagnosis #disruptors
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Conductive hearing ... PagetsDisease #pathophysiology ... #diagnosis #signs
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