The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... neurological findings #GiantCell ... #Temporal #Arteritis ... #Pathophysiology ... #Symptoms #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... Osteonecrosis Esp ... Complications #pathophysiology ... #signs #symptoms
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
) Arteritis: Clinical ... Complications Signs ... Hemorrhages #GiantCell ... #Temporal #Arteritis ... #Vasculitis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Erythematosus ... Complications #pathophysiology ... #signs #symptoms
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Posterior hip ... Signs/Symptoms ... weight-bear • Arthritic ... msk #diagnosis #pathophysiology ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... RA) or systemic lupus ... erythematosus ( ... SLE) Signs / Symptoms ... Sjogrens #Syndrome #Pathophysiology
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings
 - Morning Stiffness (>1
Giant Cell Arteritis ... Weight Loss #Temporal ... CranialArteritis #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Vasculitis
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Arthritis ... Slipped capital femoral ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Arthralgia's (common), arthritis ... and ankles) #HSP ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... blood to limbs (esp ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms