The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology complications temporal arteritis erythematosus systemic ankylosingspondylitis avascularnecrosis centralretinalartery cranialarteritis crao criteria extraarticular gastrointestinal giantcellarteritis kawasaki manifestations msk mucocutaneous
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... Erythematosus #SLE ... pathophysiology #signs ... #symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... palpation - Vasculitic ... neurological findings #GiantCell ... #Symptoms #Vasculitis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Complications Signs ... /Symptoms: - ... Hemorrhages #GiantCell ... Complications #Signs ... #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Erythematosus #SLE ... pathophysiology #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Livedo Reticularis, Vasculitis ... #SLE #Mucocutaneous ... pathophysiology #diagnosis #signs ... #symptoms #complications
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... RA) or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms ... #Symptoms
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... pseudo-widening in Sl ... pathophysiology #diagnosis #signs ... #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... interstitial lung disease ... pathophysiology #signs ... #symptoms #diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... GCA, SLE, GPA) - ... • Hematologic Disease ... ophthalmology #diagnosis #signs ... #symptoms
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... hands & feet Signs ... /Symptoms/Complications ... #Kawasaki #Disease ... #Symptoms #Vasculitis
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