Pathnologic @pathnologic
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... Lymphadenitis #HSV #Pathology ... #Microscopy #Clinical ... #LymphNode
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
Hobnail variant of PTC ... cytoplasm, hobnail cells ... #Papillary #Thyroid ... #Carcinoma #Pathology ... #Clinical #Microscopy
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology ... #LymphNode #Clinical ... #Microscopy
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
• Carcinoma cells ... around the tumor cells ... #Papillary #Thyroid ... #Cancer #Pathology ... Clinical #Gross #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical ... #Microscopy
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
from an elderly pt ... w pure red cell ... Aplasia #Parvovirus #Pathology ... #Smear #Microscopy
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... thyrotoxicosis #AIT #Pathology ... #Clinical #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Warthin-Finkeldey type giant cells ... Monocytoid B cells ... Lymphadenitis #PatternA #Pathology ... #Microscopy #LymphNode
Oncocytic Variant of Medullary Carcinoma
Don't assume every oncocytic thyroid tumor is a Hurthle cell neoplasm! Nested
every oncocytic thyroid ... tumor is a Hurthle cell ... Medullary #Carcinoma #Pathology ... #Microscopy #Clinical
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
Microscopic examination ... multinucleated giant cells ... #Clinical #Derm ... #Pathology #Herpes ... Tzsanck #Smear #Microscopy