Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
Simplex Virus Lymphadenitis ... • HSV-infected cells ... Simplex #Virus #Lymphadenitis ... Microscopy #Clinical #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
Paracoccidioides brasiliensis Lymphadenitis ... fibrosis (A) and well-formed ... seen within giant cells ... #brasiliensis #Lymphadenitis ... #Pathology #LymphNode
Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
late phase HIV lymphadenitis ... Pattern C" in HIV Lymphadenitis ... pattern C #HIV #Lymphadenitis ... Pathology #Microscopy #LymphNode
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
typical of HIV lymphadenitis ... Pattern A" in HIV Lymphadenitis ... Warthin-Finkeldey type giant cells ... Monocytoid B cells ... Pathology #Microscopy #LymphNode
Here are the morphological hallmarks of Rhabdomyosarcoma.

 - Broken arrow sign 

 - tad-pole rhabdomyoblasts
rhabdomyoblasts - Wraith cells ... - Cross striations
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
Red blood cells ... endoplasmic reticulum in cells ... Pathology #Clinical #Gross
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
• Carcinoma cells ... around the tumor cells ... Pathology #Clinical #Gross
LAMP2 cardiomyopathy in a 12-year-old boy with sudden death (Table 1; patient #1). A. At autopsy,
cardiac muscle cells ... , or groups of cells ... #Clinical #Gross