Pathnologic @pathnologic
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Path Geek - All things #pathology
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Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
The many faces of the Hodgkin/Reed-Sternberg (HRS) cell: Even as medical students we are aware of
Reed-Sternberg (HRS) cell ... Reed-Sternberg cell ... (RS cell). ... seen in every case ... Pathology #Clinical #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... Pathology #Clinical #Microscopy
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Prolymphocytes In our case ... 🔬Tumor cells are ... size lymphoid cells ... Peripheral #Pathology #Microscopy
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... #Amiodarone #thyroid ... Pathology #Clinical #Microscopy
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... Pathology #Clinical #Microscopy
Aldosteronoma — Spironolactone Bodies 

1. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and
treat hypertension caused ... Red blood cells ... endoplasmic reticulum in cells ... Clinical #Gross #Microscopy
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
Warthin-Finkeldey type giant cells ... Monocytoid B cells ... PatternA #Pathology #Microscopy ... #LymphNode #Clinical
Hepatosplenic T-cell lymphoma involving hepatic sinusoids.

HSTL also involves BM sinusoids and splenic red pulp cords and
Hepatosplenic T-cell ... essentially all cases ... present in most cases ... Hepatosplenic #TCell ... HSTCL #Pathology #Microscopy